Yohimbine is an alpha-2 antagonist sold in fat-loss supplements. A small trial in athletes reported reduced body fat, but evidence is thin and supplement labels often misstate content.
Key points
- One small randomised trial in soccer players reported body-fat reduction.
- Anxiety, raised blood pressure and tachycardia are known effects.
- Supplement analyses found frequent label inaccuracies.
- Products sold online under this name have not been independently verified; label identity and concentration cannot be assumed.
What the literature shows
Ostojic reported reduced body fat percentage in elite soccer players over 21 days versus placebo.
Cohen and colleagues analysed yohimbine supplements and found many with inaccurate labelling and some containing undeclared compounds.
What remains unknown
- Replication in larger trials.
- Interaction with stimulants and antidepressants.
Safety and monitoring implications
- People with anxiety, panic disorder or hypertension face higher risk.
- Labelled amounts may be unreliable.
Cited literature
- 1.Ostojic SM. (2006). Yohimbine: the effects on body composition and exercise performance in soccer players. Research in Sports Medicine. Find on PubMed
- 2.Cohen PA, Wang YH, Maller G, et al. (2016). Pharmaceutical quantities of yohimbine found in dietary supplements in the USA. Drug Testing and Analysis. Find on PubMed
Community reports
Anecdotal — not scientific evidence
Lived experience is valuable context and often surfaces problems before the literature does. It is also uncontrolled, unverified and subject to bias, so it never overrides published findings here.
Editorial evidence status
MixedCommunity discussion of this compound is widespread, but no independently verified reports were available for this analysis. Anecdotes have not been invented or treated as clinical evidence.
Buying Yohimbine in Australia: what to check first
APEDRA does not sell Yohimbine or any other product, and takes no commission from suppliers. If you are researching where to buy it, the biggest practical risk is not the compound itself but what is actually in the bottle: under-dosing, substitution with a different compound, and contamination are all documented in independent testing of online research chemicals.
- Ask for a batch-specific third-party lab report (HPLC/mass spectrometry), not a generic certificate.
- Check independent review platforms, not only reviews hosted on the seller's own site.
- Read the shipping, returns and refund policies before ordering.
- Be wary of prices far below the market or exaggerated results claims.
Compare Australian vendors independently · how we assess suppliers
Terms used here are defined in our glossary, and the evidence-grading scale explains what this analysis's grade means. If you believe something here is wrong, tell us.
This analysis is educational. It is not medical advice, a dosing recommendation, or an endorsement of use. Speak with a qualified medical practitioner about your circumstances.