Oxymetholone has randomised trial data in HIV-associated wasting and a long history in certain anaemias. Those supervised settings documented lean-mass gains alongside clear liver-enzyme and lipid changes, which matter more, not less, outside medical care.
Key points
- Placebo-controlled trials in HIV wasting reported gains in body weight and lean mass.
- Liver enzyme elevations were common and dose-related in trial participants.
- As a 17α-alkylated oral androgen, it carries the hepatic risk profile typical of that class.
- Products sold online under this name have not been independently verified; label identity and concentration cannot be assumed.
What the literature shows
Hengge and colleagues ran a placebo-controlled trial of oxymetholone in HIV-associated wasting, reporting improvements in weight and body cell mass but also liver-enzyme elevations that led to discontinuations at the higher dose.
Reviews of 17α-alkylated androgens associate the class with cholestasis, peliosis hepatis and, rarely, hepatic tumours, particularly with prolonged exposure.
What remains unknown
- Risk at combined or extended recreational exposure has not been studied prospectively.
- How rapidly lipid and liver changes reverse after cessation varies between individuals.
Safety and monitoring implications
- Jaundice, dark urine, itching or right-upper abdominal pain warrant prompt medical review.
- Combining with other oral hepatotoxic substances or alcohol plausibly compounds liver risk.
Cited literature
- 1.Hengge UR, Stocks K, Faulkner S, et al. (2003). Oxymetholone for the treatment of HIV-wasting: a double-blind, randomized, placebo-controlled phase III trial in eugonadal men and women. HIV Clinical Trials. Find on PubMed
- 2.Solimini R, Rotolo MC, Mastrobattista L, et al. (2017). Hepatotoxicity associated with illicit use of anabolic androgenic steroids in doping. European Review for Medical and Pharmacological Sciences. Find on PubMed
Community reports
Anecdotal — not scientific evidence
Lived experience is valuable context and often surfaces problems before the literature does. It is also uncontrolled, unverified and subject to bias, so it never overrides published findings here.
Editorial evidence status
MixedCommunity discussion of this compound is widespread, but no independently verified reports were available for this analysis. Anecdotes have not been invented or treated as clinical evidence.
Buying Oxymetholone in Australia: what to check first
APEDRA does not sell Oxymetholone or any other product, and takes no commission from suppliers. If you are researching where to buy it, the biggest practical risk is not the compound itself but what is actually in the bottle: under-dosing, substitution with a different compound, and contamination are all documented in independent testing of online research chemicals.
- Ask for a batch-specific third-party lab report (HPLC/mass spectrometry), not a generic certificate.
- Check independent review platforms, not only reviews hosted on the seller's own site.
- Read the shipping, returns and refund policies before ordering.
- Be wary of prices far below the market or exaggerated results claims.
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Terms used here are defined in our glossary, and the evidence-grading scale explains what this analysis's grade means. If you believe something here is wrong, tell us.
This analysis is educational. It is not medical advice, a dosing recommendation, or an endorsement of use. Speak with a qualified medical practitioner about your circumstances.